The Spry framework is not finished at this time. The support for accessibility is developing, and I’d love to hear comments. Feel free to post comments here or to the Spry forum on the Labs site.
Sounds pretty good, but what are the drawbacks? Page length and page weight are certainly factors to consider. If the page shows all of the data on a single page, there will be (in the case of the product demo) 150KB of images instead of 7KB and the page could be very long since it would have all of the content that is specific to each product on one page. There is the risk that the page would not be usable because of the length or page weight for some examples. Looking at the photo gallery demo I wouldn’t want all of the images from all of my photo galleries on a single page — pagination and separate galleries are useful features that help users deal with the large volume of content.