So Lion is now out. Many users will be asking how this will impact applications such as AE.
To give some insight – Adobe engineers have been testing our applications since the first drop of Lion was available to developers. In many cases, there has been a dialogue between Apple and Adobe about where issues have arisen and how to address / fix them.
For After Effects specifically – there are no known specific issues to report with CS 5 or CS 5.5 running on 10.7 Lion. There are however a few changes in the OS that you should be aware of in your production workflow (for installing applications, accessing prefs etc):
We do know of an intermittent crash on quit with AE CS 4 in Lion that was being addressed by Apple. We are working on determining if this was fixed by Apple in the final shipping version of the OS.