InDesign Secrets received a good question from an InDesign user in the Netherlands:
[W]e would like to move the preference folder of InDesign 4.0 outside this profile. I did do this for Adobe Photoshop by entering a text string into the registry, but unfortunately it does not work that way for InDesign (does it for other CS2 components?).
According to an InDesign engineer:
In CS2, preferences, caches, and temp files went into “%USERHOME%\Application Data\Adobe\InDesign\Version x.y\”. The only mitigation you can do is (via the preferencews UI) select a new folder for temporary database files to live in.
In CS3, Adobe made changes so that only files that are smaller (and actually preferences) went into what we considered the roaming part of the profile, i.e. “%USERHOME%\Application Data\Adobe\InDesign\Version x.y\”. Files that were caches or temp files now go into “%USERHOME%\Local Settings\Application Data\Adobe\InDesign\Version x.y\” which we expect to not roam.
There are, unfortunately, no hidden InDesign-specific registry entries by which users can redirect these folders at this time.