It can be challenging to fix broken cross-references in long documents — 500 pages, for example. Resolving the cross-reference(s) in the source FrameMaker file and then generating the PDF all over again isn’t the only way out. With Acrobat, you can easily fix broken cross-references in the PDF itself. Here’s how:
  1. In Acrobat 9, click Tools > Advanced Editing > Link Tool.
  2. Double-click a highlighted cross-reference.
  3. On the Action page in the Link Properties dialog, select Go to a page view from the Select Action drop-down menu. Click Add.

    4. gotoapageview.jpg

  4. Scroll to the destination page for the link and click Set Link.
See http://bit.ly/1Xpucp for the Adobe Help article on creating links in PDF files.