There have been some questions on Windows Vista support. Adobe FrameMaker 7.2 and Adobe RoboHelp 6 do not support Windows Vista. However, the next versions currently under development for both FrameMaker and RoboHelp will support Windows Vista.
Update – Adobe FrameMaker 8, Adobe RoboHelp 7 and Adobe Technical Communication Suite support Windows Vista and Office 2007. If you are publishing online help or HTML help and looking at a cross platform solution, you can download RoboHelp Packager for Adobe AIR . RoboHelp Packager for Adobe AIR generates cross-platform online help and provides two additional skins – Multi Tab Accordion and Unipane .