Adobe has worked extensively on removing dependencies on QuickTime in its professional video, audio and digital imaging applications and native decoding of many .mov formats is available today (including uncompressed, DV, IMX, MPEG2, XDCAM, h264, JPEG, DNxHD, DNxHR, AVCI and Cineform). Native export support is also possible for DV and Cineform in .mov wrappers.
Unfortunately, there are some codecs which remain dependent on QuickTime being installed on Windows, most notably Apple ProRes. We know how common this format is in many workflows, and we continue to work hard to improve this situation, but have no estimated timeframe for native decode currently.
Other commonly used QuickTime formats which would be affected by the uninstallation of QuickTime include Animation (import and export), DNxHD/HR (export) as would workflows where growing QuickTime files are being used (although we strongly advise using MXF for this wherever possible).
Adobe’s desire has always been to support everything natively without the need for QuickTime. As a result of the above we intend to increase our efforts to remove these incompatibilities, and provide our customers with a complete native pipeline. We will provide more information on this as we progress.